Human B2M FCGRT Stable CHOK1 Cell Line

Introduction

CHOK1 cell line stable expressing exogenous human B2M gene and FCGRT gene

Application

Drug screening and biological assays

Background

FCGRT (Fc Fragment of IgG Receptor And Transporter) encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. Diseases associated with FCGRT include Selective Igg Deficiency Disease and Immunodeficiency.

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