Human CCR4 Stable 293T Cell Line
| Catalog Number |
CBCL-366 |
| Price |
Online Inquiry |
| Unit Quantity |
1x106 cells / 1.0 ml |
Introduction
Stable HEK293T cell line expressing exogenous human CCR4 gene
Application
Drug screening and biological assays
Background
CCR4 is a G protein-linked seven transmembrane domain chemokine receptor mainly expressed by T cells, and function as a chemoattractant homing receptor on circulating memory lymphocytes through interaction with its two ligands, CCL17 and CCL22. CCR4 is also widely expressed on malignant T cells and Tregs in the skin and peripheral blood of patients with allergic diseases, and regarded as a potential therapeutic target for cutaneous T-cell lymphoma (CTCL) and atopic dermatitis and bronchial asthma.
Product Information
| Species |
Human |
| Host Cell Line |
293T |
| Cell Type |
Human embryonic kidney cells |
| Stability |
Stable in culture over 10 passages |
| Growth Properties |
Adherent |
| Pharmaceutical Target |
Immune Molecules |
| Recommended Medium |
DMEM + 10% FBS + 1 μg/ml Puromycin |
| Selection Marker |
Puromycin |
| Morphology |
Monolayer |
| Seeding Density |
Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio |
Recommended a ratio of 1:4-1:5. |
| Storage Method |
Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Doubling Time |
Approximately 30 hours |
| QC |
WB |
| Biosafety Level |
BSL-1 |
| Shipping |
Shipping in dry ice |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
