Human CCR8 Stable MC38 Cell Line
| Catalog Number | CBCL-291 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
Introduction
Stable MC38 clone expressing exogenous human CCR8 gene
Application
Drug screening and biological assays
Background
CCR8, also known as CD198, is a member of the chemokine receptor subfamily and belongs to the G-protein coupled receptor, which is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues.
Product Information
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Human CCR8 Stable MC38 Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Mouse |
| Host Cell Line | MC38 |
| Cell Type | Mouse colon cancer cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Selection Marker | Puromycin |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:10. |
| Doubling Time | Approximately 20 hours |
| Recommended Medium | RPMI 1640 + 10% FBS + 5 μg/ml Puromycin |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.