Human CD123 Stable C1498 Cell Line
| Catalog Number |
CBCL-279 |
| Price |
Online Inquiry |
| Unit Quantity |
1x106 cells / 1.0 ml |
Introduction
Stable C1498 cell line expressing exogenous human CD123 gene
Application
Drug screening and biological assays
Background
CD123, also known as Interleukin-3 receptor, is a glycoprotein member of the hematopoietic receptor superfamily. CD123 associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. CD123 has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
Product Information
| Species |
Mouse |
| Host Cell Line |
C1498 |
| Cell Type |
Lymphocytic leukemia, Lymphoblast |
| Stability |
Stable in culture over 10 passages |
| Growth Properties |
Suspension |
| Pharmaceutical Target |
Immune Molecules |
| Recommended Medium |
RPMI1640 + 10% FBS + 5 μg/ml Puromycin |
| Selection Marker |
Puromycin |
| Morphology |
Lymphoblast |
| Seeding Density |
Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio |
Recommended a ratio of 1:4-1:5. |
| Storage Method |
Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Doubling Time |
Approximately 40 hours |
| QC |
WB |
| Biosafety Level |
BSL-1 |
| Shipping |
Shipping in dry ice |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
