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Human CD123 Stable C1498 Cell Line

Catalog Number CBCL-279
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

Stable C1498 cell line expressing exogenous human CD123 gene

Application

Drug screening and biological assays

Background

CD123, also known as Interleukin-3 receptor, is a glycoprotein member of the hematopoietic receptor superfamily. CD123 associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. CD123 has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name Human CD123 Stable C1498 Cell Line
Pharmaceutical Target Immune Molecules
Species Mouse
Host Cell Line C1498
Cell Type Lymphocytic leukemia, Lymphoblast
Morphology lymphoblastoid
Growth Properties Suspension
Selection Marker Puromycin
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:5.
Doubling Time Approximately 40 hours
Recommended Medium RPMI1640 + 10% FBS + 5 μg/ml Puromycin
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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