| Catalog Number | CBCL-579 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
CT26.WT cell line stable expressing exogenous human CD20 gene
Drug screening and biological assays
CD20 (MS4A1) is a glycosylated phosphoprotein mainly expressed on the cell surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. CD20 is a highly attractive target antigen of several approved monoclonal or bispecific antibodies, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune disease.
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Human CD20 Stable CT26.WT Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Mouse |
| Host Cell Line | CT26 |
| Cell Type | Mouse colon cancer cell line |
| Morphology | Monolayer |
| Growth Properties | Adherent |
| Selection Marker | Puromycin |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:4-1:10. |
| Recommended Medium | RPMI1640 + 10% FBS + 10 μg/ml Puromycin |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |