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Human CLDN18.1 Stable CHOK1 Cell Line

Catalog Number CBCL-536
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

CHOK1 cell line stable expressing exogenous human CLND18 gene isoform 1

Application

Drug screening and biological assays

Background

CLDN18.1 is the isoform 1 of the claudin 18 gene, which belong to the lager claudin family and play the important role in cell tight junction in epithelial cells. The other isoform, CLND18.2, is found overexpressed on gastrointestinal adenocarcinoma and pancreatic tumors. The identification as a tumor target of CLDN18.2 has led to the repaid progress of antibody treatment of gastrointestinal adenocarcinoma and pancreatic tumors.

Product Information

Species Mouse
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Stability Stable in culture over 10 passages
Growth Properties Adherent
Pharmaceutical Target Immune Molecules
Recommended Medium F12K + 10% FBS + 6 μg/ml Puromycin
Selection Marker Puromycin
Morphology Epithelial
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:8.
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Doubling Time Approximately 24 hours
QC WB
Biosafety Level BSL-1
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.
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