Catalog Number | CBCL-536 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
CHOK1 cell line stable expressing exogenous human CLND18 gene isoform 1
Drug screening and biological assays
CLDN18.1 is the isoform 1 of the claudin 18 gene, which belong to the lager claudin family and play the important role in cell tight junction in epithelial cells. The other isoform, CLND18.2, is found overexpressed on gastrointestinal adenocarcinoma and pancreatic tumors. The identification as a tumor target of CLDN18.2 has led to the repaid progress of antibody treatment of gastrointestinal adenocarcinoma and pancreatic tumors.
Category | Immune Molecules Cell Lines |
Cell Line Name | Human CLDN18.1 Stable CHOK1 Cell Line |
Pharmaceutical Target | Immune Molecules |
Species | Hamster |
Host Cell Line | CHOK1 |
Cell Type | Chinese hamster ovary cell line |
Morphology | Epithelial |
Growth Properties | Adherent |
Selection Marker | Puromycin |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:4-1:8. |
Doubling Time | Approximately 24 hours |
Recommended Medium | F12K + 10% FBS + 6 μg/ml Puromycin |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Stability | Stable in culture over 10 passages |
QC | WB |
Shipping | Shipping in dry ice |
Biosafety Level | BSL-1 |
Caution | For Research Use Only |