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Human CLDN18.2 Stable CT26.WT Cell Line

Catalog Number CBCL-539
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

CT26.WT cell line stable expressing exogenous human CLDN18 gene isoform 2

Application

Drug screening and biological assays

Background

CLDN18.2 is the isoform 2 of the claudin 18 gene, which belong to the lager claudin family and play the important role in cell tight junction in epithelial cells. The identification as a tumor target of CLDN18.2 has led to the repaid progress of antibody treatment of gastrointestinal adenocarcinoma and pancreatic tumors.

Product Information

Species Mouse
Host Cell Line CT26.WT
Cell Type Mouse colon adenocarcinoma cell line
Stability Stable in culture over 10 passages
Growth Properties Adherent
Pharmaceutical Target Immune Molecules
Recommended Medium RPMI1640 + 10% FBS + 1 μg/ml Puromycin
Selection Marker Puromycin
Morphology Monolayer
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:10.
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Doubling Time
QC WB
Biosafety Level BSL-1
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.
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