Human CLDN18.2 Stable MKN45 Cell Line
| Catalog Number |
CBCL-380 |
| Price |
Online Inquiry |
| Unit Quantity |
1x106 cells / 1.0 ml |
Introduction
Stable MKN45 cell line expressing exogenous human CLDN18 gene isoform2
Application
Drug screening and biological assays
Background
CLDN18.2 is the isoform 2 of the claudin 18 gene, which belong to the lager claudin family and play the important role in cell tight junction in epithelial cells. The identification as a tumor target of CLDN18.2 has led to the repaid progress of antibody treatment of gastrointestinal adenocarcinoma and pancreatic tumors.
Product Information
| Category |
Immune Molecules Cell Lines |
| Cell Line Name |
Human CLDN18.2 Stable MKN45 Cell Line |
| Pharmaceutical Target |
Immune Molecules |
| Species |
Human |
| Host Cell Line |
MKN45 |
| Cell Type |
Human gastric adenocarcinoma cell line |
| Morphology |
Spindle-shaped；Oval |
| Growth Properties |
Adherent |
| Selection Marker |
Puromycin and hygromycin B |
| Seeding Density |
Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio |
Recommended a ratio of 1:3-1:5. |
| Doubling Time |
Approximately 60 hours |
| Recommended Medium |
RPMI1640 + 10% FBS + 1 μg/ml Puromycin |
| Storage Method |
Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability |
Stable in culture over 10 passages |
| QC |
WB |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
