Human EGFR vlll Stable 293T Cell Line

Introduction

HEK293T cell line stable expressing exogenous human EGFR gene vlll isoform

Application

Drug screening and biological assays

Background

EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase, and activated by binding of its specific ligand, such as epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha), EGFR overexpression or overactivity have associated with a number of cancers, including the lung cancer and colon cancer. The identification of EGFR as a driver gene has led to the development of anticancer therapeutics agents.

Product Information