Human ERBB3 Stable CHOK1 Cell Line

Catalog Number	CBCL-617
Price	Online Inquiry
Unit Quantity	1x10⁶ cells / 1.0 ml

Introduction

Stable CHOK1 cell line expressing exogenous human INSR gene

Application

Drug screening and biological assays

Background

ERBB3, also known as HER3, is a transmembrane protein belonging to epidermal growth factor receptor (ERBB) family of receptor tyrosine kinase. The kinase domain impaired ERBB3 can from active heterodimer with other member of ERBB family, this heterodimer, mostly with ERBB2 after binding with its ligand NRG1 or NRG2, play an important role in cancer growth, invasion, metastasis and chemotherapeutic resistant.

Product Information

Species	Mouse
Host Cell Line	CHOK1
Cell Type	Chinese hamster ovary cell line
Stability	Stable in culture over 10 passages
Growth Properties	Adherent
Pharmaceutical Target	Immune Molecules
Recommended Medium	F12K + 10% FBS + 6 μg/ml Puromycin
Selection Marker	Puromycin
Morphology	Monolayer
Seeding Density	Thaw entire contents into an appropriate T25 flask.
Subculture Ratio	Recommended a ratio of 1:4-1:8.
Storage Method	Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Doubling Time	Approximately 24 hours
QC	WB
Biosafety Level	BSL-1
Shipping	Shipping in dry ice
Caution	For Research Use Only

For research use only. Not for any other purpose.