Catalog Number | CBCL-444 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
HEK293T cell line stable expressing exogenous human ICOS gene
Drug screening and biological assays
D278 or ICOS (Inducible T-cell Costimulatory) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells. It is thought to be important for Th2 cells in particular. It forms homodimers and plays an important role in cell-cell signaling, immune responses and regulation of cell proliferation.
Species | Human |
Host Cell Line | 293T |
Cell Type | Human embryonic kidney cells |
Stability | Stable in culture over 10 passages |
Growth Properties | Adherent |
Pharmaceutical Target | Immune Molecules |
Recommended Medium | DMEM + 10% FBS + 0.5 μg/ml Puromycin |
Selection Marker | Puromycin |
Morphology | Monolayer |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:4-1:5. |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Doubling Time | Approximately 30 hours |
QC | WB |
Biosafety Level | BSL-1 |
Shipping | Shipping in dry ice |
Caution | For Research Use Only |