| Catalog Number | CBCL-464 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
HEK293T cell line stable expressing exogenous human LAIR-1 gene
Drug screening and biological assays
LAIR-1 (leukocyte associated immunoglobulin like receptor 1, CD305) is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. By blocking the binding of LAIR-1, LAIR-1 inhibitors can promote T cell function and dendritic cell activity, which could result in anti-tumor immune responses that eliminate cancer cells.
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Human LAIR-1 Stable 293T Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Human |
| Host Cell Line | 293T |
| Cell Type | Human embryonic kidney cells |
| Morphology | Monolayer |
| Growth Properties | Adherent |
| Selection Marker | Puromycin |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:4-1:5. |
| Doubling Time | Approximately 30 hours |
| Recommended Medium | DMEM + 10% FBS + 0.5 μg/ml Puromycin |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |