Human LAIR-1 Stable 293T Cell Line

Introduction

HEK293T cell line stable expressing exogenous human LAIR-1 gene

Application

Drug screening and biological assays

Background

LAIR-1 (leukocyte associated immunoglobulin like receptor 1, CD305) is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. By blocking the binding of LAIR-1, LAIR-1 inhibitors can promote T cell function and dendritic cell activity, which could result in anti-tumor immune responses that eliminate cancer cells.

Product Information