Catalog Number | CBCL-600 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
Stable HEK293T cell line expressing exogenous human LILRB2 gene
Drug screening and biological assays
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) belongs to the leukocyte immunoglobulin-like receptor (LIR) family of transmembrane glycoproteins that negatively regulate immune cell activation.LILRB2 is expressed on both innate (monocytes, macrophages, basophils, and DCs) and adaptive (CD4+ T cells) immune cells and interacts with MHC-I on nucleated cells (unknown specific ligand). LILRB2 interacts with related ligands HLA-G, ANGPTLs, SEMA4A and CD1d in tumor microenvironment, resulting in myeloid cells promoting tumor growth and enhancing tumor immune escape.
Species | Human |
Host Cell Line | 293T |
Cell Type | Human embryonic kidney cell |
Stability | Stable in culture over 10 passages |
Growth Properties | Suspension |
Pharmaceutical Target | Immune Molecules |
Recommended Medium | DMEM + 10% FBS + 1 μg/ml Puromycin |
Selection Marker | Puromycin |
Morphology | Monolayer |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:4-1:5. |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Doubling Time | Approximately 30 hours |
QC | WB |
Biosafety Level | BSL-1 |
Shipping | Shipping in dry ice |
Caution | For Research Use Only |