Catalog Number | CBCL-334 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
Stable MDCK cell line expressing exogenous human MDR1 gene
Drug screening and biological assays
MDR1, also known as ABCB1, is a glycoprotein which is a well-characterized ABC-transporter of the MDR/TAP subfamily. MDR1 is an important protein of the cell membrane that pumps many foreign substances out of cells, and itisan ATP-dependent efflux pump with broad substrate specificity. MDR1 is expressed primarily in certain cell types in the liver, pancreas, kidney, colon, and jejunum. MDR1 is also found in brain capillary endothelial cells.
Category | Immune Molecules Cell Lines |
Cell Line Name | Human MDR1 Stable MDCK Cell Line |
Pharmaceutical Target | Immune Molecules |
Species | Dog |
Host Cell Line | MDCK |
Cell Type | Dog canine kidney cells |
Morphology | Monolayer |
Growth Properties | Adherent |
Selection Marker | Puromycin |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:4-1:5. |
Recommended Medium | DMEM + 10% FBS + 2 μg/ml Puromycin |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Stability | Stable in culture over 10 passages |
QC | WB |
Shipping | Shipping in dry ice |
Biosafety Level | BSL-1 |
Caution | For Research Use Only |