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Human OX40 Stable 293T Cell Line

Catalog Number CBCL-470
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

HEK293T cell line stable expressing exogenous human OX40 gene

Application

Drug screening and biological assays

Background

OX40, also named as CD134 or tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), is a member of the TNFR superfamily acting as co-stimulatory immune checkpoint molecule expressed on the activated T cells. OX40 plays a critical role in maintaining of immune response and lead to a memory immune response. OX40-OX40 Ligand interaction is involved in allergic airway inflammation, graft-versus-host disease and autoimmune disease and cardiovascular disease.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name Human OX40 Stable 293T Cell Line
Pharmaceutical Target Immune Molecules
Species Human
Host Cell Line 293T
Cell Type Human embryonic kidney cells
Morphology Monolayer
Growth Properties Adherent
Selection Marker Puromycin
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:5.
Doubling Time Approximately 30 hours
Recommended Medium DMEM + 10% FBS + 0.5 μg/ml Puromycin
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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