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Human PD1-Middle Stable CHOK1 Cell Line

Catalog Number CBCL-283
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

Stable CHOK1 cell line expressing exogenous human PD1 gene

Application

Drug screening and biological assays

Background

PD-1, also named CD279, is a receptor belonging to immunoglobulin superfamily which is expressed primarily on activated T cells. NK cells, B cells, and monocytes. PD-1 interaction with its ligands, PD-L1 and PD-L2, leads to downregulation of T cell responses, including T cell proliferation and cytokine production, and limits immune-destruction of tissues. The interaction between PD-1 and its ligands, thus plays a role in maintaining the balance between immune activation and tolerance, potentially including tumor tolerance.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name Human PD1-Middle Stable CHOK1 Cell Line
Pharmaceutical Target Immune Molecules
Species Hamster
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Selection Marker Puromycin
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:5.
Doubling Time Approximately 30 hours
Recommended Medium RPMI1640 + 10% FBS + 10 μg/ml Puromycin
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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