Human PDL1 Stable MC38 Cell Line

Introduction

Stable MC38 clone expressing exogenous human PDL1 gene

Application

Drug screening and biological assays

Background

PD-L1, also called human programed cell death ligand 1, is a transmembrane protein that play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease, virus infection and cancer. PD-L1 binds to its receptor PD-1 on activated T cells, B cells, and myeloid cells, to modulate activation or inhibition. Upregulation of PD-L1 can allow cancer cell to evade the host immune system.

Product Information