Human PVRL4 Stable PC3 Cell Line

Catalog Number	CBCL-326
Price	Online Inquiry
Unit Quantity	1x10⁶ cells / 1.0 ml

Introduction

Stable PC-3 cell line expressing exogenous human PVRL4 gene

Application

Drug screening and biological assays

Background

PVRL4, also known as nectin-4, is a type-I transmembrane glycoprotein that belongs to the nectin family and promotes cell-cell adhesion by serving as a major component of adherens junctions. Nectin-4 is overexpressed in a variety of human solid tumors of the pancreas, breast, lung, and ovary. Due to its restricted expression pattern in normal human tissues, Nectin-4 may serve as a novel diagnostic and therapeutic target for a variety of human tumors.

Product Information

Species	Human
Host Cell Line	PC-3
Cell Type	Human carcinoma of prostate cell line
Stability	Stable in culture over 10 passages
Growth Properties	Adherent
Pharmaceutical Target	Immune Molecules
Recommended Medium	DMEM + 10% FBS + 1 μg/ml Puromycin
Selection Marker	Puromycin
Morphology	Epithelial
Seeding Density	Thaw entire contents into an appropriate T25 flask.
Subculture Ratio	Recommended a ratio of 1:4-1:5.
Storage Method	Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Doubling Time
QC	WB
Biosafety Level	BSL-1
Shipping	Shipping in dry ice
Caution	For Research Use Only

For research use only. Not for any other purpose.