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Human PVRL4 Stable PC3 Cell Line

Catalog Number CBCL-326
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

Stable PC-3 cell line expressing exogenous human PVRL4 gene

Application

Drug screening and biological assays

Background

PVRL4, also known as nectin-4, is a type-I transmembrane glycoprotein that belongs to the nectin family and promotes cell-cell adhesion by serving as a major component of adherens junctions. Nectin-4 is overexpressed in a variety of human solid tumors of the pancreas, breast, lung, and ovary. Due to its restricted expression pattern in normal human tissues, Nectin-4 may serve as a novel diagnostic and therapeutic target for a variety of human tumors.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name Human PVRL4 Stable PC3 Cell Line
Pharmaceutical Target Immune Molecules
Species Human
Host Cell Line PC-3
Cell Type Human carcinoma of prostate cell line
Morphology Epithelial
Growth Properties Adherent
Selection Marker Puromycin
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:5.
Recommended Medium DMEM + 10% FBS + 1 μg/ml Puromycin
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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