| Catalog Number | CBCL-589 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
CHOK1 cell line stable expressing exogenous human SIGLEC10 gene
Drug screening and biological assays
SIGLEC10, alsonamed sialic acid binding Ig like lectin 10, is a member of siglecs, immunoglobulin super family lectins with a defining feature of recognizing sialic acid-containing structures. Since most of the siglec family members contain ITIM-or ITIM-like motifs and many are known to be associated with SHP-1 and/or SHP-214, it has been suggested that the siglec family member may serve as a negative regulatory pathway for cellular activation.
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Human SIGLEC10 Stable CHOK1 Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Selection Marker | Puromycin |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:4-1:5. |
| Doubling Time | Approximately 24 hours |
| Recommended Medium | F12K + 10% FBS + 6 μg/ml Puromycin |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |