| Catalog Number | CBCL-626 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
MC38 cell line stable expressing exogenous mouse siglec15 gene
Drug screening and biological assays
Siglec-15 is a transmembrane glycoprotein, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding lg-like lectin) family, and is found primarily on the surface of immune cells. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Human Siglec15 Stable MC38 Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Mouse |
| Host Cell Line | MC38 |
| Cell Type | Mouse colon cancer cell line |
| Morphology | Monolayer |
| Growth Properties | Adherent |
| Selection Marker | Puromycin |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:4-1:10. |
| Recommended Medium | RPMI1640 + 10% FBS + 5 μg/ml Puromycin |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |