Human Siglec8 Stable CHOK1 Cell Line
| Catalog Number | CBCL-517 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
Introduction
Stable CHOK1 cell line expressing exogenous human INSR gene
Application
Drug screening and biological assays
Background
Siglec8, also named as SAF2, is a transmembrane protein belonging to siglec family, and mainly expressed in human eosinophils, mast cells. Recent studies show that siglec8 is involved in allergic disease, and its monodonal antibody, lirentelimab has been evaluated as a treatment for eosinophilic gastritis and duodenitis ina randomized dinical trial.
Product Information
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Human Siglec8 Stable CHOK1 Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Monolayer |
| Growth Properties | Adherent |
| Selection Marker | Puromycin |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:4-1:8. |
| Doubling Time | Approximately 24 hours |
| Recommended Medium | F12K + 10% FBS + 10 μg/ml Puromycin |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.