Human TREM1-DAP12 Stable 293T Cell Line
| Catalog Number |
CBCL-401 |
| Price |
Online Inquiry |
| Unit Quantity |
1x106 cells / 1.0 ml |
Introduction
Stable HEK293T cell line expressing exogenous human TREM1-DAP12 gene
Application
Drug screening and biological assays
Background
TREM1, full named as Triggering receptor expressed on myeloid cells 1, is an immunoglobulin (Ig) superfamily transmembrane protein which is expressed on myeloid cells. TREM1 forms a complex with transmembrane adaptor DAP12 and then mediates signaling and cell activation after binding serval ligands. TREM1 expression is higher in tumor vs non-tumor tissues, likely due to its expression by myeloid cells that infiltrate tumors, and is also believed to be a promising target for cancer therapy.
Product Information
| Species |
Human |
| Host Cell Line |
293T |
| Cell Type |
Human embryonic kidney cells |
| Stability |
Stable in culture over 10 passages |
| Growth Properties |
Adherent |
| Pharmaceutical Target |
Immune Molecules |
| Recommended Medium |
DMEM + 10% FBS + 1 μg/ml Puromycin |
| Selection Marker |
Puromycin and hygromycin B |
| Morphology |
Monolayer |
| Seeding Density |
Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio |
Recommended a ratio of 1:4-1:5. |
| Storage Method |
Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Doubling Time |
Approximately 30 hours |
| QC |
WB |
| Biosafety Level |
BSL-1 |
| Shipping |
Shipping in dry ice |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
