Human TREM1-DAP12 Stable 293T Cell Line
| Catalog Number |
CBCL-401 |
| Price |
Online Inquiry |
| Unit Quantity |
1x106 cells / 1.0 ml |
Introduction
Stable HEK293T cell line expressing exogenous human TREM1-DAP12 gene
Application
Drug screening and biological assays
Background
TREM1, full named as Triggering receptor expressed on myeloid cells 1, is an immunoglobulin (Ig) superfamily transmembrane protein which is expressed on myeloid cells. TREM1 forms a complex with transmembrane adaptor DAP12 and then mediates signaling and cell activation after binding serval ligands. TREM1 expression is higher in tumor vs non-tumor tissues, likely due to its expression by myeloid cells that infiltrate tumors, and is also believed to be a promising target for cancer therapy.
Product Information
| Category |
Immune Molecules Cell Lines |
| Cell Line Name |
Human TREM1-DAP12 Stable 293T Cell Line |
| Pharmaceutical Target |
Immune Molecules |
| Species |
Human |
| Host Cell Line |
293T |
| Cell Type |
Human embryonic kidney cells |
| Morphology |
Monolayer |
| Growth Properties |
Adherent |
| Selection Marker |
Puromycin and hygromycin B |
| Seeding Density |
Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio |
Recommended a ratio of 1:4-1:5. |
| Doubling Time |
Approximately 30 hours |
| Recommended Medium |
DMEM + 10% FBS + 1 μg/ml Puromycin |
| Storage Method |
Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability |
Stable in culture over 10 passages |
| QC |
WB |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
