Human TREM2-DAP12 Stable 293T Cell Line

Catalog Number	CBCL-391
Price	Online Inquiry
Unit Quantity	1x10⁶ cells / 1.0 ml

Introduction

Stable HEK293T cell line expressing exogenous human TREM2-DAP12 gene

Application

Drug screening and biological assays

Background

TERM2 is a membrane protein which expressed primarily in immune cells across many different tissues, and form a receptor signaling complex with TYROBP, also named as DAP12, then mediates signaling and cell activation after binding serval ligands, it plays an important role in different inflammatory diseases, especially Alzheimer's disease, and is also believed as a promising target for cancer therapy.

Product Information

Species	Human
Host Cell Line	293T
Cell Type	Human embryonic kidney cells
Stability	Stable in culture over 10 passages
Growth Properties	Adherent
Pharmaceutical Target	Immune Molecules
Recommended Medium	DMEM + 10% FBS + 0.5 μg/ml Puromycin
Selection Marker	Puromycin and hygromycin B
Morphology	Monolayer
Seeding Density	Thaw entire contents into an appropriate T25 flask.
Subculture Ratio	Recommended a ratio of 1:4-1:5.
Storage Method	Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Doubling Time	Approximately 30 hours
QC	WB
Biosafety Level	BSL-1
Shipping	Shipping in dry ice
Caution	For Research Use Only

For research use only. Not for any other purpose.