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Human TRKA Stable CHOK1 Cell Line

Catalog Number CBCL-480
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

CHOK1 cell line stable expressing exogenous human TRKA gene

Application

Drug screening and biological assays

Background

NTRK1, also named Tropomyosin receptor kinase A(TrkA), is the high affinity catalytic receptor for the neurotrophin and play a major role in neuronal differentiation and survival. The overactivation or overexpression of NTRK1 fusion protein, due to chromosomal rearrangement, was originally found in congenital fibrosarcoma and subsequently found in secretory breast cancer and other type cancer.

Product Information

Species Mouse
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Stability Stable in culture over 10 passages
Growth Properties Adherent
Pharmaceutical Target Immune Molecules
Recommended Medium F12K + 10% FBS + 6 μg/ml Puromycin
Selection Marker Puromycin
Morphology Epithelial
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:8.
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Doubling Time Approximately 24 hours
QC WB
Biosafety Level BSL-1
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.
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