Jurkat-Human BTLA (Luc)-Reporter Cell
| Catalog Number | CBCL-0232 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
Introduction
The Human BTLA (Luc) Jurkat Reporter Cell was engineered to express the NFAT response element driving luciferase expression and the full-length human BTLA receptor (Uniprot: Q7Z6A9 1). Co-culture with an anti-human BTLA agonist antibody can result in decreased TCR signaling and NFAT-mediated luminescence.
Application
Screen for anti-human BTLA agonist antibody.
Background
BTLA is an immune checkpoint receptor that inhibits T cell activation and proliferation. It plays a role in maintaining immune tolerance and preventing autoimmune diseases.
Product Information
| Category | Luciferase Reporter Cell Lines |
| Cell Line Name | Jurkat-Human BTLA (Luc)-Reporter Cell |
| Protein Family | B and T lymphocyte attenuator family |
| Gene | BTLA |
| Species | Human |
| Host Cell Line | Jurkat |
| Cell Type | Human T-cell leukemia |
| Morphology | Lymphoblastoid |
| Growth Properties | Suspension |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.