Jurkat-Human CD32b (Luc)-Reporter Cell
| Catalog Number | CBCL-0240 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
Introduction
This cell line is a Jurkat-based reporter cell line engineered to express the NFAT response element-driven luciferase expression system and the full-length human CD32b (Uniprot: P31994-1). It is used to evaluate the ADCP activity of antibodies in the presence of corresponding target cells.
Application
Determination of ADCP activity induced by antibodies.
Background
CD32b is a low-affinity Fc gamma receptor that inhibits immune cell activation and plays a role in maintaining immune tolerance.
Product Information
| Category | Luciferase Reporter Cell Lines |
| Cell Line Name | Jurkat-Human CD32b (Luc)-Reporter Cell |
| Protein Family | Fc gamma receptor family |
| Gene | CD32b |
| NCBI Gene ID | 2214 |
| Species | Human |
| Host Cell Line | Jurkat |
| Cell Type | Human T-cell leukemia |
| Morphology | Lymphoblastoid |
| Growth Properties | Suspension |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.