Jurkat-Human NKp46 (Luc)-Reporter Cell
| Catalog Number |
CBCL-0254 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
This Jurkat reporter cell line expresses both the NFAT response element driving luciferase expression and the full-length human NKp46 receptor (Uniprot: O76036-1). When co-cultured with an anti-human NKp46 agonist antibody, the interaction between the agonist antibody and NKp46 on the cell surface results in NFAT-mediated luminescence.
Application
Screen for anti-human NKp46 agonist antibody.
Background
NKp46 is a natural cytotoxicity receptor expressed on natural killer (NK) cells that mediates target cell recognition and killing.
Product Information
| Category |
Luciferase Reporter Cell Lines |
| Cell Line Name |
Jurkat-Human NKp46 (Luc)-Reporter Cell |
| Protein Family |
Natural killer cell protein 46 family |
| Gene |
NKp46 |
| NCBI Gene ID |
9437 |
| Species |
Human |
| Host Cell Line |
Jurkat |
| Cell Type |
Human T-cell leukemia |
| Morphology |
Lymphoblastoid |
| Growth Properties |
Suspension |
| Selection Marker |
Puromycin (5 μg/mL) + Hygromycin B (20 μg/mL) |
| Recommended Medium |
RPMI-1640 + 10% FBS |
| Freeze Medium |
Serum-free cell cryopreservation medium |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
