Jurkat-NFAT-Luc2-PD1-TIGIT-PVRIG-Stable Cell Line
| Catalog Number | CBCL-0504 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The Jurkat-NFAT-Luc2-PD1-TIGIT-PVRIG-Stable Cell Line is a stable clone of the Jurkat-NFAT-Luc2 cell line that expresses the exogenous PD1, TIGIT, and PVRIG genes.
Application
Drug screening and biological assays
Background
LAG3 (Lymphocyte-activation gene 3) is an immune checkpoint receptor expressed on activated T-cells and natural killer cells. It negatively regulates T-cell activation and proliferation, and its blockade can enhance anti-tumor immune responses.
Product Information
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Jurkat-NFAT-Luc2-PD1-TIGIT-PVRIG-Stable Cell Line |
| Protein Family | Programmed cell death protein 1 family; T cell immunoreceptor with Ig and ITIM domains family; Poliovirus receptor-related family |
| Gene | PD1; TIGIT; PVRIG |
| NCBI Gene ID | 3902 |
| Species | Human |
| Host Cell Line | Jurkat |
| Cell Type | Human T-cell leukemia |
| Morphology | Lymphoblastoid |
| Growth Properties | Suspension |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.