Jurkat-NFAT-Luc2-PD1-TIGIT-PVRIG-Stable Cell Line
| Catalog Number |
CBCL-0504 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The Jurkat-NFAT-Luc2-PD1-TIGIT-PVRIG-Stable Cell Line is a stable clone of the Jurkat-NFAT-Luc2 cell line that expresses the exogenous PD1, TIGIT, and PVRIG genes.
Application
Drug screening and biological assays
Background
LAG3 (Lymphocyte-activation gene 3) is an immune checkpoint receptor expressed on activated T-cells and natural killer cells. It negatively regulates T-cell activation and proliferation, and its blockade can enhance anti-tumor immune responses.
Product Information
| Category |
Immune Molecules Cell Lines |
| Cell Line Name |
Jurkat-NFAT-Luc2-PD1-TIGIT-PVRIG-Stable Cell Line |
| Protein Family |
Programmed cell death protein 1 family; T cell immunoreceptor with Ig and ITIM domains family; Poliovirus receptor-related family |
| Gene |
PD1; TIGIT; PVRIG |
| NCBI Gene ID |
3902 |
| Species |
Human |
| Host Cell Line |
Jurkat |
| Cell Type |
Human T-cell leukemia |
| Morphology |
Lymphoblastoid |
| Growth Properties |
Suspension |
| Selection Marker |
Puromycin, Hygromycin B, G418 |
| Recommended Medium |
RPMI1640+10%FBS +0.5µg/mL Puromycin + 300µg/mL Hygromycin B + 500µg/mL G418 |
| Freeze Medium |
70% RPMI1640+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
