Catalog Number | CBCL-625 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
Stable 293T cell line expressing exogenous human LILRB3 gene
Drug screening and biological assays
LILRB3, also known as CD85A, is a member of the leukocyte immunoglobulin sample (LIR) family, which is expressed on immune cells and bone marrow, where it binds to MHC class I molecules on antigen-presenting cells and transduces negative signals that inhibit stimulation of the immune response. LILRB3 is thought to control inflammation and cytotoxicity to help focus immune responses and limit autoreactivity. Diseases associated with LILRB3 include Takayasu Arteritis and Anencephaly.
Species | Human |
Host Cell Line | 293T |
Cell Type | Human embryonic kidney cells |
Stability | Stable in culture over 10 passages |
Growth Properties | Adherent |
Pharmaceutical Target | Immune Molecules |
Recommended Medium | DMEM + 10% FBS + 1 μg/ml Puromycin |
Selection Marker | Puromycin |
Morphology | Epithelial |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:4-1:5. |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Doubling Time | Approximately 30 hours |
QC | WB |
Biosafety Level | BSL-1 |
Shipping | Shipping in dry ice |
Caution | For Research Use Only |