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MC38-mouse PDL1-Stable Cell Line

Catalog Number CBCL-0501
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Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

The MC38-mouse PDL1-Stable Cell Line is a stable clone of the MC38 cell line that expresses the exogenous mouse PDL1 gene.

Application

Drug screening and biological assays

Background

PDL1 (Programmed Death-Ligand 1) is an immune checkpoint protein that is expressed on the surface of tumor cells and some immune cells. It binds to its receptor PD-1 on T-cells, inhibiting T-cell activation and promoting immune tolerance, which helps tumors evade immune surveillance.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name MC38-mouse PDL1-Stable Cell Line
Protein Family Programmed cell death ligand 1 family
Gene PDL1
NCBI Gene ID 29126
Species Mouse
Host Cell Line MC38
Cell Type Mouse colorectal carcinoma
Morphology Epithelial
Growth Properties Adherent
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.