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MC38-mouse PDL1-Stable Cell Line

Catalog Number CBCL-0501
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

The MC38-mouse PDL1-Stable Cell Line is a stable clone of the MC38 cell line that expresses the exogenous mouse PDL1 gene.

Application

Drug screening and biological assays

Background

PDL1 (Programmed Death-Ligand 1) is an immune checkpoint protein that is expressed on the surface of tumor cells and some immune cells. It binds to its receptor PD-1 on T-cells, inhibiting T-cell activation and promoting immune tolerance, which helps tumors evade immune surveillance.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name MC38-mouse PDL1-Stable Cell Line
Protein Family Programmed cell death ligand 1 family
Gene PDL1
NCBI Gene ID 29126
Species Mouse
Host Cell Line MC38
Cell Type Mouse colorectal carcinoma
Morphology Epithelial
Growth Properties Adherent
Recommended Medium (MEM+0.01mM NEAA)+10%FBS
Freeze Medium 70% MEM+20% FBS+10% DMSO
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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