MC38-PD1-LAG3-Stable Cell Line
| Catalog Number | CBCL-0407 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The MC38-PD1-LAG3-Stable Cell Line is a stable clone of the MC38 cell line that expresses the exogenous PD1 and LAG3 genes.
Application
Drug screening and biological assays
Background
PD-1 (Programmed Death-1) is an immune checkpoint receptor expressed on activated T-cells. It binds to its ligands PD-L1 and PD-L2, inhibiting T-cell activation and promoting immune tolerance, which is exploited by tumors to evade immune surveillance.
Product Information
| Category | Immune Molecules Cell Lines |
| Cell Line Name | MC38-PD1-LAG3-Stable Cell Line |
| Protein Family | Programmed cell death protein 1 family; Lymphocyte activation gene-3 family |
| Gene | PD1; LAG3 |
| NCBI Gene ID | PD1（PDCD1）：5133；LAG3：3902 |
| Species | Mouse |
| Host Cell Line | MC38 |
| Cell Type | Mouse colorectal carcinoma |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.