MC38-PDL1-CLDN18.2-OS8-Stable Cell Line
| Catalog Number |
CBCL-0436 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The MC38-PDL1-CLDN18.2-OS8-Stable Cell Line is a stable clone of the MC38 cell line that expresses the exogenous PDL1, CLDN18.2, and OS8 genes.
Application
Drug screening and biological assays
Background
PDL1 is an immune checkpoint ligand; CLDN18.2 is a splice variant of claudin 18, expressed on gastric and pancreatic cancer cells. Co-targeting PDL1 and CLDN18.2 may enhance antitumor immune responses.
Product Information
| Category |
Immune Molecules Cell Lines |
| Cell Line Name |
MC38-PDL1-CLDN18.2-OS8-Stable Cell Line |
| Protein Family |
Programmed cell death ligand 1 family; Claudin family |
| Gene |
PDL1; CLDN18.2 |
| NCBI Gene ID |
PDL1（PDCD1LG1）：29126；CLDN18.2（CLDN18 亚型相关，CLDN18：51208 ） |
| Species |
Mouse |
| Host Cell Line |
MC38 |
| Cell Type |
Mouse colorectal carcinoma |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Puromycin |
| Recommended Medium |
RPMI1640+10%FBS+5µg/mL Puromycin |
| Freeze Medium |
70% RPMI1640+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
