MC38-PDL1-CLDN18.2-OS8-Stable Cell Line
| Catalog Number | CBCL-0436 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The MC38-PDL1-CLDN18.2-OS8-Stable Cell Line is a stable clone of the MC38 cell line that expresses the exogenous PDL1, CLDN18.2, and OS8 genes.
Application
Drug screening and biological assays
Background
PDL1 is an immune checkpoint ligand; CLDN18.2 is a splice variant of claudin 18, expressed on gastric and pancreatic cancer cells. Co-targeting PDL1 and CLDN18.2 may enhance antitumor immune responses.
Product Information
| Category | Immune Molecules Cell Lines |
| Cell Line Name | MC38-PDL1-CLDN18.2-OS8-Stable Cell Line |
| Protein Family | Programmed cell death ligand 1 family; Claudin family |
| Gene | PDL1; CLDN18.2 |
| NCBI Gene ID | PDL1（PDCD1LG1）：29126；CLDN18.2（CLDN18 亚型相关，CLDN18：51208 ） |
| Species | Mouse |
| Host Cell Line | MC38 |
| Cell Type | Mouse colorectal carcinoma |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.