MIAPaCa2-KRAS-G12C-HiBiT-1B4-Cell Line
| Catalog Number |
CBCL-0348 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
This MIAPaCa2 cell line has been engineered to express the HiBiT tag fused to the KRAS G12C mutant protein, enabling the study of KRAS G12C dynamics and interactions in real-time using bioluminescence imaging.
Application
Drug screening and biological assays
Background
KRAS G12C is a specific point mutation in the KRAS proto-oncogene, which is frequently found in various cancers and leads to constitutive activation of the KRAS protein.
Product Information
| Category |
Fluorescence Labeled Cell Lines |
| Cell Line Name |
MIAPaCa2-KRAS-G12C-HiBiT-1B4-Cell Line |
| Protein Family |
GTPase family |
| Gene |
KRAS G12C |
| NCBI Gene ID |
3845 |
| Species |
Human |
| Host Cell Line |
MIAPaCa2 |
| Cell Type |
Human pancreatic adenocarcinoma |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
DMEM+10%FBS+2.5%HS |
| Freeze Medium |
70% DMEM+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
