MM.1S-eGFP/Firefly Luciferase BCMA Knockout-Stable Cell Line
| Catalog Number |
CBCL-0732 |
| Price |
Online Inquiry |
| Unit Quantity |
2 x 10^6 cells / 1.0 ml |
Introduction
The MM.1S-eGFP/Firefly Luciferase BCMA Knockout-Stable Cell Line is a MM.1S cell line that constitutively expresses firefly luciferase and enhanced GFP (eGFP) under the control of a CMV promoter. BCMA has been genetically removed using CRISPR/Cas9 genome editing.
Application
Drug screening and biological assays
Background
BCMA (B - Cell Maturation Antigen), also known as TNFRSF17 (Tumor Necrosis Factor Receptor Superfamily Member 17), is a cell surface receptor expressed mainly on mature B cells and plasma cells. It plays a role in B - cell survival, proliferation, and differentiation, and is a target for therapeutic interventions in multiple myeloma and other B - cell malignancies.
Product Information
| Category |
Cell Signaling Cell Lines |
| Cell Line Name |
MM.1S-eGFP/Firefly Luciferase BCMA Knockout-Stable Cell Line |
| Protein Family |
Luciferase family; B-cell maturation antigen family |
| Gene |
eGFP; Firefly Luciferase; BCMA |
| NCBI Gene ID |
608 |
| Species |
Human |
| Host Cell Line |
MM.1S |
| Cell Type |
Human multiple myeloma |
| Morphology |
Lymphoblastoid |
| Growth Properties |
Adherent |
| Recommended Medium |
RPMI-1640 medium + 10% FBS |
| Freeze Medium |
90% FBS + 10% DMSO |
| Storage Method |
Liquid Nitrogen |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
