MM.1S-eGFP/Firefly Luciferase BCMA Knockout-Stable Cell Line
| Catalog Number | CBCL-0732 |
| Price | Online Inquiry |
| Unit Quantity | 2 x 10^6 cells / 1.0 ml |
Introduction
The MM.1S-eGFP/Firefly Luciferase BCMA Knockout-Stable Cell Line is a MM.1S cell line that constitutively expresses firefly luciferase and enhanced GFP (eGFP) under the control of a CMV promoter. BCMA has been genetically removed using CRISPR/Cas9 genome editing.
Application
Drug screening and biological assays
Background
BCMA (B - Cell Maturation Antigen), also known as TNFRSF17 (Tumor Necrosis Factor Receptor Superfamily Member 17), is a cell surface receptor expressed mainly on mature B cells and plasma cells. It plays a role in B - cell survival, proliferation, and differentiation, and is a target for therapeutic interventions in multiple myeloma and other B - cell malignancies.
Product Information
| Category | Cell Signaling Cell Lines |
| Cell Line Name | MM.1S-eGFP/Firefly Luciferase BCMA Knockout-Stable Cell Line |
| Protein Family | Luciferase family; B-cell maturation antigen family |
| Gene | eGFP; Firefly Luciferase; BCMA |
| NCBI Gene ID | 608 |
| Species | Human |
| Host Cell Line | MM.1S |
| Cell Type | Human multiple myeloma |
| Morphology | Lymphoblastoid |
| Growth Properties | Adherent |
| Storage Method | Liquid Nitrogen |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.