Mouse CD70 Stable 293T Cell Line

Introduction

Stable HEK293T cell line expressing exogenous mouse CD70 gene

Application

Drug screening and biological assays

Background

CD70, also known as TNFSF7, is a type II transmembrane glycoprotein belonging to the TNF superfamily and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invioved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells.

Product Information