Mouse TREM2-DAP12 Stable 293T Cell Line

Introduction

Stable 293T cell line expressing exogenous mouse TREM2 and DAP12 gene

Application

Drug screening and biological assays

Background

TERM2, full named as Triggering receptor expressed on myeloid cells 2, is a membrane protein which expressed primarily in immune cells across many different tissues, and form a receptor signaling complex with TYROBP, also named as DAP12, then mediates signaling and cell activation after binding serval ligands, it plays an important role in different inflammatory diseases, especially Alzheimer's disease, and is also believed as a promising target for cancer therapy.

Product Information