OS8 human PVR Stable 293T Cell Line
| Catalog Number | CBCL-312 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
Introduction
Stable HEK293T cell line expressing exogenous human PVR gene
Application
Drug screening and biological assays
Background
The poliovirus receptor PVR, also known as CD155 or NECL-5. PVR mediates natural killer cell adhesion and triggers its effector function, participates in mediating tumor cell infiltration and migration, and is the attachment receptor of poliovirus. PVR expression was associated with an unfavorable prognosis in solid tumors such as colon cancer, breast cancer, lung adenocarcinoma, pancreatic cancer, melanoma, and glioblastoma.
Product Information
| Category | Immune Molecules Cell Lines |
| Cell Line Name | OS8 human PVR Stable 293T Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Human |
| Host Cell Line | 293T |
| Cell Type | Human embryonic kidney cells |
| Morphology | Monolayer |
| Growth Properties | Adherent |
| Selection Marker | Puromycin & Hygromycin B |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:4-1:5. |
| Doubling Time | Approximately 30 hours |
| Recommended Medium | RPMI1640 + 10% FBS + 1 μg/ml Puromycin + 150 μg/ml Hygromycin B |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.