| Catalog Number | CBCL-594 |
| Price | Online Inquiry |
| Unit Quantity | 1x106 cells / 1.0 ml |
Stable T47D cell clone resistant to CDK4/6 inhibitors
Drug screening and biological assays
Palbociclib, branded as Ibrance, is a selective inhibitor of cyclin-dependent inhibitor of CDK4 and CDK6, and was approved for treatment of HR-positive and HER2 negative breast cancer.
| Category | Immune Molecules Cell Lines |
| Cell Line Name | Palbociclib Resistant Stable T47D Cell Line |
| Pharmaceutical Target | Immune Molecules |
| Species | Human |
| Host Cell Line | T47D |
| Cell Type | Mammary gland epithelial cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Seeding Density | Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio | Recommended a ratio of 1:3-1:5. |
| Recommended Medium | RPMI1640 + 10% FBS + 0.2 U/ml insulin + 5 μM Palbociclib |
| Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Stability | Stable in culture over 10 passages |
| QC | WB |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |