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Palbociclib Resistant Stable T47D Cell Line

Catalog Number CBCL-594
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

Stable T47D cell clone resistant to CDK4/6 inhibitors

Application

Drug screening and biological assays

Background

Palbociclib, branded as Ibrance, is a selective inhibitor of cyclin-dependent inhibitor of CDK4 and CDK6, and was approved for treatment of HR-positive and HER2 negative breast cancer.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name Palbociclib Resistant Stable T47D Cell Line
Pharmaceutical Target Immune Molecules
Species Human
Host Cell Line T47D
Cell Type Mammary gland epithelial cells
Morphology Epithelial
Growth Properties Adherent
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:3-1:5.
Recommended Medium RPMI1640 + 10% FBS + 0.2 U/ml insulin + 5 μM Palbociclib
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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