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PVR Stable CT26 Cell Line

Catalog Number CBCL-392
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

Stable CT26 cell line expressing exogenous human PVR gene

Application

Drug screening and biological assays

Background

The poliovirus receptor PVR, also known as CD155 or NECL-5. PVR mediates natural killer cell adhesion and triggers its effector function, participates in mediating tumor cell infiltration and migration, and is the attachment receptor of poliovirus. PVR expression was associated with an unfavorable prognosis in solid tumors such as colon cancer, breast cancer, lung adenocarcinoma, pancreatic cancer, melanoma, and glioblastoma.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name PVR Stable CT26 Cell Line
Pharmaceutical Target Immune Molecules
Species Mouse
Host Cell Line CT26
Cell Type Mouse colon cancer cell line
Morphology Epithelial
Growth Properties Adherent
Selection Marker Puromycin and hygromycin B
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:5.
Doubling Time Approximately 30 hours
Recommended Medium DMEM + 10% FBS + 10 μg/ml Puromycin
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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