THP-1-PDL1-Stable Cell Line
| Catalog Number |
CBCL-0514 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The THP-1-PDL1-Stable Cell Line is a stable clone of the THP-1 cell line that expresses the exogenous PDL1 gene.
Application
Drug screening and biological assays
Background
PDL1 (Programmed Death-Ligand 1) is an immune checkpoint protein that is expressed on the surface of tumor cells and some immune cells. It binds to its receptor PD-1 on T-cells, inhibiting T-cell activation and promoting immune tolerance, which helps tumors evade immune surveillance.
Product Information
| Category |
Immune Molecules Cell Lines |
| Cell Line Name |
THP-1-PDL1-Stable Cell Line |
| Protein Family |
Programmed cell death ligand 1 family |
| Gene |
PDL1 |
| NCBI Gene ID |
29126 |
| Species |
Human |
| Host Cell Line |
THP1 |
| Cell Type |
Human acute monocytic leukemia |
| Morphology |
Monocytic |
| Growth Properties |
Suspension |
| Selection Marker |
Puromycin |
| Recommended Medium |
RPMI 1640 + 10% FBS + 5μg/mL Puromycin |
| Freeze Medium |
70% RPMI 1640 + 20% FBS + 10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
