THP1-IDH2-GFP-Cell Line
| Catalog Number | CBCL-0353 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
This THP1 cell line expresses the IDH2 protein fused to green fluorescent protein (GFP), allowing for the visualization of IDH2 localization and dynamics within the cell.
Application
Drug screening and biological assays
Background
IDH2 (Isocitrate Dehydrogenase 2) is an enzyme involved in the citric acid cycle, catalyzing the oxidative decarboxylation of isocitrate to alpha-ketoglutarate.
Product Information
| Category | Fluorescence Labeled Cell Lines |
| Cell Line Name | THP1-IDH2-GFP-Cell Line |
| Protein Family | Isocitrate dehydrogenase family |
| Gene | IDH2 |
| NCBI Gene ID | 3418 |
| Species | Human |
| Host Cell Line | THP1 |
| Cell Type | Human acute monocytic leukemia |
| Morphology | Monocytic |
| Growth Properties | Suspension |
| Selection Marker | Puromycin |
| Recommended Medium | RPMI1640+10%FBS+1µg/mL Puromycin |
| Freeze Medium | 70% RPMI1640+20% FBS+10% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.