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THP1-IDH2-GFP-Cell Line

Catalog Number CBCL-0353
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

This THP1 cell line expresses the IDH2 protein fused to green fluorescent protein (GFP), allowing for the visualization of IDH2 localization and dynamics within the cell.

Application

Drug screening and biological assays

Background

IDH2 (Isocitrate Dehydrogenase 2) is an enzyme involved in the citric acid cycle, catalyzing the oxidative decarboxylation of isocitrate to alpha-ketoglutarate.

Product Information

Category Fluorescence Labeled Cell Lines
Cell Line Name THP1-IDH2-GFP-Cell Line
Protein Family Isocitrate dehydrogenase family
Gene IDH2
NCBI Gene ID 3418
Species Human
Host Cell Line THP1
Cell Type Human acute monocytic leukemia
Morphology Monocytic
Growth Properties Suspension
Selection Marker Puromycin
Recommended Medium RPMI1640+10%FBS+1µg/mL Puromycin
Freeze Medium 70% RPMI1640+20% FBS+10% DMSO
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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