THP1-IDH2-R172K-GFP-Cell Line
| Catalog Number |
CBCL-0355 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
This THP1 cell line expresses exogenous human GFP and IDH2 with R172K mutation, enabling the visualization of this mutant's localization and dynamics within the cell.
Application
Drug screening and biological assays
Background
IDH2 R172K is another point mutation in the IDH2 gene, also leading to the production of 2-hydroxyglutarate and associated with tumorigenesis.
Product Information
| Category |
Fluorescence Labeled Cell Lines |
| Cell Line Name |
THP1-IDH2-R172K-GFP-Cell Line |
| Protein Family |
Isocitrate dehydrogenase family |
| Gene |
IDH2 R172K |
| NCBI Gene ID |
3418 |
| Species |
Human |
| Host Cell Line |
THP1 |
| Cell Type |
Human acute monocytic leukemia |
| Morphology |
Monocytic |
| Growth Properties |
Suspension |
| Selection Marker |
Puromycin |
| Recommended Medium |
RPMI1640+10%FBS+1µg/mL Puromycin |
| Freeze Medium |
70% RPMI1640+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
