THP1-NFκb-Luc2-Stable Cell Line
| Catalog Number |
CBCL-0311 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
This stable THP-1 cell line expresses exogenous luciferase under the control of the NF-κB signaling pathway, enabling studies of NF-κB-dependent gene expression and signaling events.
Application
Drug screening and biological assays
Background
NFκB (Nuclear Factor kappa-light-chain-enhancer of activated B cells) is a protein complex that plays a key role in regulating the immune response to infection, inflammation, and cell survival.
Product Information
| Category |
Luciferase Reporter Cell Lines |
| Cell Line Name |
THP1-NFκb-Luc2-Stable Cell Line |
| Protein Family |
Nuclear factor kappa-light-chain-enhancer of activated B cells family |
| Gene |
NFκb |
| NCBI Gene ID |
4790 |
| Species |
Human |
| Host Cell Line |
THP1 |
| Cell Type |
Human acute monocytic leukemia |
| Morphology |
Monocytic |
| Growth Properties |
Suspension |
| Selection Marker |
HygromycinB |
| Recommended Medium |
RPMI1640+10%FBS+500µg/mL Hygromycin B |
| Freeze Medium |
70% RPMI1640+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
