TMEM87B-MERTK Stable Ba/F3 Cell Line

Catalog Number	CBCL-192
Price	Online Inquiry
Unit Quantity	1x10⁶ cells / 1.0 ml

Introduction

Stable Ba/F3 clone expressing exogenous MEM87B-MERTK fusion gene.

Application

Drug screening and biological assays

Background

MERTK is recepter tyrosine kinase beloging to TYRO3/AXL/MER (TAM) receptor kinase family, transduces signals from the extracellular matrix after binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Ba/F3, a murine interleukin-3 dependent pro-B cell line is increasingly popular as a model system for assessing both the potency and downstream signaling of kinase oncogenes, and the ability of small-molecule kinase inhibitors to block kinase activity.

Product Information

Species	Mouse
Host Cell Line	Ba/F3 cell line
Cell Type	Pro-B cells
Stability	Stable in culture over 10 passages
Growth Properties	Suspension
Pharmaceutical Target	Kinases
Recommended Medium	RPMI 1640 + 10% FBS
Selection Marker	Puromycin
Morphology	Mostly round
Seeding Density	Thaw entire contents into an appropriate T25 flask.
Subculture Ratio	Recommended a ratio of 1:10.
Storage Method	Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Doubling Time	Approximately 20 hours
QC	WB
Biosafety Level	BSL-1
Shipping	Shipping in dry ice
Caution	For Research Use Only

For research use only. Not for any other purpose.